Analyzing Monday’s Jacksonville Jaguars at Buffalo Bills odds and lines, with expert NFL picks and predictions.

After an all-out sprint through their first two games and having two wins to show for it, the Bills have had 10 full days to ...

Mitch Morse expects a “different opportunity” when he experiences Highmark Stadium as a visitor for the first time ...

Bills/Sabres owner Terry Pegula is thankful to have Guelli in place, and Guelli hopes this is the final stop of a journey ...

Josh Allen has a losing regular season record against just three NFL teams. One is the Jacksonville Jaguars. Allen is 1-2 in ...

Week 3 of the NFL season is here, and the Buffalo Bills are preparing to host the Jacksonville Jaguars on Monday Night ...

First, it was Tua Tagovailoa going down with a concussion in the Bills win last Thursday. Now, it's backup quarterback Skylar ...

The Jaguars average 4.0 fewer points per game (15.0) than the Bills allow (19.0). Jacksonville averages just 15.5 fewer yards ...

Also keep in mind that Buffalo has been one of the league’s best teams on both sides of the ball so far, ranking third in ...

Buffalo Bills running back James Cook could be the key to the AFC East champs continuing their early season dominance.

Our computer prediction projects a lopsided win (28-14) for the Buffalo Bills (2-0) over the Jacksonville Jaguars (0-2) on ...

ORCHARD PARK, N.Y. — The Buffalo Bills face the Jacksonville Jaguars for a week three matchup on Monday night. This game will be the Bills' first home primetime battle of the season. The Channel 2 ...