or RAD51C/D mutations, according to findings from the Phase I/IIa PETRA study. In February 2024, Capivasertib combined with docetaxel to enhance anti-tumour activity through inhibition of AKT ...

Launching a Multiplex BRCA1/RAD51C ddPCR Methylation Assay as a Clinical HRD Test Dr. Elizabeth Swisher, professor in the Division of Gynecologic Oncology at the University of Washington School of ...

Observation that loss of RAD51C gene methylation contributes to PARP inhibitor resistance in RAD51C-methylated ovarian cancer, along with the striking observation that as few as 1 cell in 6,000 with ...

Internal political squabbles — and the fallout from a global backlash to inflation, immigration and ruling elites — are hobbling Germany and France. By Jim Tankersley and Aurelien Breeden ...

The president-elect’s call for Taiwan to spend more on its own defense and his complaints about its semiconductor dominance may herald a tenser relationship. By Chris Buckley and Amy Chang ...

Why are the two often so disconnected? And what role can technology play in integrating them? A new CMS accountable care program aims to drive progress, and one expert explains what it means for ...

Nov. 8, 2024 — Researchers identify a key pathway leading to neurodegeneration in early stages of ALS, hinting at the potential for short-circuiting the progression of the fatal disease if ...

Nov. 1, 2024 — Microplastics have been steadily increasing in freshwater environments for decades and are directly tied to rising global plastic production since the 1950s, according to a new ...

Amit Shah vows anti-conversion law in Maharashtra, opposition caste census Union Home Minister Amit Shah, during the release of BJP's election manifesto in Mumbai, promised a stringent anti ...